Aptuit has invested in a Thermo Fisher 16 twin screw extruder, adding Hot Melt Extrusion Technology (HME), to its range of technologies for processing poorly soluble drugs. HME can offer enhanced dissolution and bioavailability, sustained drug release over an extended period of time, conversion of raw materials into a uniform shape and density, and can be used in continuous wet granulation.   Dr. Jonathan Goldman, chief executive officer, Aptuit, said, “The poor solubility of new chemical ...